Brooke is basically lobotomized before Claire kills her. Neela has her tongue cut out before being killed. Maggie has her hands chopped off, then her arms before Claire finishes her off.
The puzzle in the home economics room also counts as this.
However, he's finally dealt with his guilt over Serena, and he's promised to live life to the fullest, chasing his dreams and not falling into despair since he saw what despair did to Dolores. All three of Kyle's potential prom dates are dead, so all Kyle can do is put a stop to Dolores's bloodshed, and Kyle thinks he may never date again.